current research topics in virology

Virology News

Top headlines, latest headlines.

• Avian Flu: Elephant Seal Colony Declines
• Improving Deer Health One Test at a Time
• Animal Viruses With Potential to Infect Humans
• H5N1 Virus Isolated from Infected Dairy Worker
• RSV Vaccines Effective
• Polar Bears' Exposure to Pathogens
• Cellular Superhero Protects Us from RNA Viruses
• Novel Antibody Platform Tackles Viral Mutations
• Ancient Viral DNA in Human Genome: MS, ALS
• How Coronavirus Defeats Innate Immune Response

Earlier Headlines

Thursday, november 14, 2024.

• Revolutionizing Biology Education: Scientists Film 'giant' Mimivirus in Action

Wednesday, November 6, 2024

• Washington Coast Avian Flu Outbreak Devastated Caspian Terns, Jumped to Seals

Monday, October 21, 2024

• Unexpected Beauty, Major Antimicrobial Power Boost as Phages Form Into Surprising Flower Shapes

Thursday, October 17, 2024

• Big Data, Real World, Multi-State Study Finds RSV Vaccine Highly Effective in Protecting Older Adults Against Severe Disease, Hospitalization and Death
• New mRNA Vaccine Created to Prevent and Treat C. Difficile
• Identifying the Genes That Viruses 'steal' From Ocean Microbes

Wednesday, October 16, 2024

• 'Two for the Price of One' Scientists Discover New Process to Drive Anti-Viral Immunity

Wednesday, October 9, 2024

• Viruses Are Teeming on Your Toothbrush, Showerhead
• Over 160,000 New Viruses Discovered by AI

Tuesday, October 8, 2024

• In a Warming World, Public Needs to Know More About Protections from Mosquito-Borne Illnesses
• Scientists Discover Novel Series of SARS-CoV-2 Mpro Inhibitors for Potential New COVID-19 Treatments
• Rates of a Tick-Borne Parasitic Disease Are on the Rise

Tuesday, October 1, 2024

• New Mouse Models Offer Valuable Window Into COVID-19 Infection
• New Images of RSV May Expose Stubborn Virus's Weak Points

Wednesday, September 25, 2024

• Pigs May Be Transmission Route of Rat Hepatitis E to Humans
• A Viral Close-Up of HTLV-1

Tuesday, September 24, 2024

• Fruit-Only Diet Improves Bats' Immune Response to Viruses
• Good Nutrition Boosts Honey Bee Resilience Against Pesticides, Viruses

Monday, September 23, 2024

• Compact 'gene Scissor' Enables Effective Genome Editing

Friday, September 20, 2024

• A Two-Dose Schedule Could Make HIV Vaccines More Effective
• Researchers Discover Immune Response to Dengue Can Predict Risk of Severe Reinfections
• New Testing System Using Janus Particles Rapidly and Accurately Detects COVID-19

Thursday, September 19, 2024

• Genetic Tracing at the Huanan Seafood Market Further Supports COVID Animal Origins
• Coronavirus Spike Proteins Can Be Selectively Detected in 5 Minutes
• Stopping Plants from Passing Viruses to Their Progeny

Tuesday, September 17, 2024

• Paving the Way for Antivirals Against Ebola Virus and Its Deadly Relatives

Monday, September 16, 2024

• 'Food Theft' Among Seabirds Could Be Transmission Point for Deadly Avian Flu

Thursday, September 12, 2024

• Targeted Immune Intervention and Stopping ART in Model of SIV Infection Leads to Control of Viral Replication and Reservoirs
• Smart Supramolecular Assemblies
• Researchers Develop Promising Lassa Fever Vaccine

Wednesday, September 11, 2024

• Avian Flu Found in Wastewater of 10 Texas Cities Through Virome Sequencing

Tuesday, September 10, 2024

• An Antidiabetic Helps the Immune System Recognize Reservoirs of HIV
• Study Identifies Areas of Europe at Risk from Dengue Fever Due to Spread of Asian Tiger Mosquito

Monday, September 9, 2024

• Hep C: We're Closer Than Ever to Solving Mystery of Deadly Virus

Friday, September 6, 2024

• Hijacking the Command Center of the Cell: Nuclear Parasites in Deep-Sea Mussels

Wednesday, September 4, 2024

• Immune Cells Prevent Lung Healing After Viral Infection
• Kidney Disease in Cats: High-Quality Feline iPSCs Generated Without Genetic Footprint
• Newly Discovered Viruses in Parasitic Nematodes Could Change Our Understanding of How They Cause Disease
• Investigational Mpox mRNA Vaccine Reduces Disease Severity in Primates Compared to Available Vaccines
• H5 Influenza Vaccines: What Needs to Be Done to Reduce the Risk of a Pandemic

Tuesday, September 3, 2024

• Dangerous Airborne Fungus Boosted by California Droughts

Wednesday, August 28, 2024

• How Beetle Juice Led to the Discovery of a Virus and Solved the Mystery of a Superworm Die-Off
• Study Reveals Isolation, Endogamy and Pathogens in Early Medieval Spanish Community

Monday, August 26, 2024

• Gut Bacteria Composition Influences Rotavirus Vaccine Efficacy
• Immune System That Bacteria Use to Respond to Viral Infections

Thursday, August 22, 2024

• Universal Flu Vaccine Candidate Protects Against Infection in Mice

Wednesday, August 21, 2024

• Next Time You Beat a Virus, Thank Your Microbial Ancestors
• Honey Bees May Play Key Role in Spreading Viruses to Wild Bumblebees

Monday, August 19, 2024

• New Insights on How Bird Flu Crosses the Species Barrier
• Low Cortisol, Hair-Trigger Stress Response in the Brain May Underlie Long COVID

Monday, August 12, 2024

• Study Reveals Oleoyl-ACP-Hydrolase Underpins Lethal Respiratory Viral Disease

Sunday, August 11, 2024

• The Threat of Mpox Has Returned, but Public Knowledge About It Has Declined

Friday, August 9, 2024

• New Two-Step Flu Vaccine Strategy Shows Promise in Pig Model
• Bacteria Encode Hidden Genes Outside Their Genome--Do We?

Thursday, August 8, 2024

• 3D Bioprinting Advances Research on Respiratory Viruses
• Microscopy Technique 'paves Way' For Improving Understanding of Cellular Functions
• Recurrent Wheezing in Children Linked to 'silent' Viral Infections

Wednesday, August 7, 2024

• Asthma Emergencies Spike When Allergenic Pollen Blooms
• Viral Defense Protein Speeds Up Female Stem Cell Production

Monday, August 5, 2024

• Why Virus Causing Cold Sores Does Not Spread to Devastating Brain Infection

Friday, August 2, 2024

• Discovery of a New Population of Macrophages Promoting Lung Repair After Viral Infections
• Coinfecting Viruses Impede Each Other's Ability to Enter Cells
• Genetic Signatures of Domestication Identified in Pigs, Chickens

Thursday, August 1, 2024

• Novel Nanosensing Technique for Quality Control of Viral Vectors in Gene Therapy

Wednesday, July 31, 2024

• Nasal COVID-19 Vaccine Halts Transmission, Animal Study Finds
• Scientists Capture Immune Cells Hidden in Nasal Passages

Tuesday, July 30, 2024

• What Shapes a Virus's Pandemic Potential? SARS-CoV-2 Relatives Yield Clues

Monday, July 29, 2024

• Fetal Brain Impacted When Mom Fights Severe Flu: New Mouse Study Explains How
• New Progress in Research Into Malignant Catarrhal Fever in Cattle
• Virus That Causes COVID-19 Is Widespread in Wildlife, Scientists Find

Friday, July 26, 2024

• Seven Steps to Achieving the Right to Clean Indoor Air Post-Pandemic

Thursday, July 25, 2024

• New Drug Shows Promise in Clearing HIV from Brain
• Scientists Identify Key Protein Behind Spread of Shingles Virus
• How Evolution Tamed a Deadly Virus and Why We Should Still Worry

Wednesday, July 24, 2024

• Proof-of-Concept Study to Find Functional Cure for HIV
• New Study Confirms Mammal-to-Mammal Avian Flu Spread

Tuesday, July 23, 2024

• New Rapid Method for Determining Virus Infectivity

Monday, July 22, 2024

• Exposing Dengue's Invasion Strategies

Thursday, July 18, 2024

• Secrets Behind Viral Precision

Wednesday, July 17, 2024

• Ancient Viruses Fuel Modern-Day Cancers
• Influenza Viruses Can Use Two Ways to Infect Cells
• Llama Nanobodies: A Breakthrough in Building HIV Immunity
• 'Sacrifice' Of Virus Data Clears the Path to Open a Disease Discovery Pipeline

Tuesday, July 16, 2024

• Ancient Microbes Offer Clues to How Complex Life Evolved

Monday, July 15, 2024

• Receptors Make Dairy Cows a Prime Target for Influenza

Thursday, July 11, 2024

• Wild Plants and Crops Don't Make Great Neighbors, Research Finds

Wednesday, July 10, 2024

• Big Gain in Battle Against Harmful Bacteria

Monday, July 8, 2024

• Raw Milk Is Risky, but Airborne Transmission of H5N1 from Cow's Milk Is Inefficient in Mammals
• New Bio-Based Tool Quickly Detects Concerning Coronavirus Variants

Thursday, July 4, 2024

• Not So Selfish After All: Viruses Use Freeloading Genes as Weapons

Wednesday, July 3, 2024

• Pasteurization Inactivates Highly Infectious Avian Flu in Milk, Study Suggests

Tuesday, July 2, 2024

• Advancing Toward a Preventative HIV Vaccine

Thursday, June 27, 2024

• Bird Flu Stays Stable on Milking Equipment for at Least One Hour
• A Promising Weapon Against Measles

Wednesday, June 26, 2024

• New Tool Enables Faster, More Cost-Effective Genome Editing of Traits to Improve Agriculture Sustainability

Friday, June 21, 2024

• Simple Test for Flu Could Improve Diagnosis and Surveillance
• Cannabis Use Tied to Increased Risk of Severe COVID-19

Wednesday, June 19, 2024

• Blessing in Disguise: Mycoviruses Enhance Fungicide Effectiveness Against Plant Pathogens
• Wooden Surfaces May Have Natural Antiviral Properties

Friday, June 14, 2024

• Infectious H5N1 Influenza Virus in Raw Milk Rapidly Declines With Heat Treatment
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Virology articles within Nature Medicine

Research Briefing | 06 November 2024

HIV-1 remission following stem cell transplant without CCR5Δ32 mutation

We report the first case of a person achieving sustained HIV-1 remission after transplantation with allogeneic hematopoietic stem cells that express wild-type CCR5 and thus are permissive to HIV-1 infection. The 53-year-old man received the transplant in 2018 to treat a rare myeloid sarcoma and has not experienced viral rebound since discontinuing antiretroviral therapy in November 2021.

News & Views | 26 September 2024

The practical longevity of stockpiled A(H5N1) influenza vaccine

Stockpiled A(H5N1) influenza vaccines made using viruses from the mid-2000s stimulate antibodies that cross-react with current strains, despite being separated by 20 years of viral evolution — supporting investment in vaccine stockpiling for pandemic preparedness.

• Richard J. Webby

Article | 18 September 2024

Human outbreaks of a novel reassortant Oropouche virus in the Brazilian Amazon region

Genomic and epidemiologic analyses revealed that a novel reassortant viral lineage of the Oropouche virus, which has been circulating in the western Amazon region of Brazil for about a decade, is associated with the recent human outbreaks between 2022 and 2024.

• Felipe Gomes Naveca
• , Tatiana Amaral Pires de Almeida
•  &  Gonzalo Bello

Article 12 September 2024 | Open Access

Safety and antiviral effect of a triple combination of HIV-1 broadly neutralizing antibodies: a phase 1/2a trial

In a first-in-human trial of a triple combination of broadly neutralizing antibodies in people living with HIV, 83% of participants maintained virologic suppression for the duration of antibody therapy, with 42% showing virologic suppression for at least 38–44 weeks, despite the decline of serum antibody concentrations to low or undetectable levels.

• , Victoria E. K. Walker-Sperling
•  &  Dan H. Barouch

Article 02 September 2024 | Open Access

Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells

HIV remission was achieved for 32 months after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells.

• Asier Sáez-Cirión
• , Anne-Claire Mamez
•  &  Alexandra Calmy

Review Article | 09 August 2024

Long COVID science, research and policy

This Review outlines the current state of scientific evidence on long COVID, discusses its impacts on patients, health systems, economies and global health metrics, and proposes a forward-looking research and policy roadmap.

• Ziyad Al-Aly
• , Hannah Davis
•  &  Eric J. Topol

Article 30 May 2024 | Open Access

Three-year outcomes of post-acute sequelae of COVID-19

Analyses from the US Department of Veterans Affairs databases reported residual elevated risk and health burden of long COVID at 3 years in hospitalized individuals after SARS-CoV-2 infection.

•  &  Ziyad Al-Aly

Brief Communication | 06 February 2024

Severe disease during both primary and secondary dengue virus infections in pediatric populations

In an analysis of severe dengue cases in a cohort of children in India, more than half could be attributed to primary rather than secondary infection, suggesting that primary dengue infections might also contribute substantially to severe disease burden.

• Charu Aggarwal
• , Hasan Ahmed
•  &  Kaja Murali-Krishna

Research Briefing | 23 November 2023

Viral, cellular and immune aspects of non-suppressible HIV-1 viremia

We find that people with non-suppressible human immunodeficiency virus (HIV) viremia despite antiretroviral therapy (ART) exhibit several distinguishing features. These include expanded CD4 + T cell clones containing HIV proviruses integrated into transcriptionally permissive regions, the presence of certain proviral defects or human leukocyte antigen (HLA)-escape mutations, enhanced survival signatures, and muted interferon and cytotoxic CD8 + T cell responses.

Article 13 November 2023 | Open Access

Viral and host mediators of non-suppressible HIV-1 viremia

Understanding the heterogeneity of HIV infection, such as in persons with non-suppressible HIV-1 viremia despite adherence to antiretroviral treatment, is crucial to better tailor therapeutic interventions to abrogate HIV-1 persistence.

• Abbas Mohammadi
• , Behzad Etemad
•  &  Jonathan Z. Li

Article 04 October 2023 | Open Access

Pleconaril and ribavirin in new-onset type 1 diabetes: a phase 2 randomized trial

Results from the DiViD Intervention, a phase 2 randomized, placebo-controlled trial, showed that antiviral treatment with pleconaril and ribavirin for 6 months resulted in higher endogenous insulin production in children and adolescents with new-onset type 1 diabetes.

• Lars Krogvold
• , Ida Maria Mynarek
•  &  Knut Dahl-Jørgensen

Article 14 September 2023 | Open Access

Distinct monkeypox virus lineages co-circulating in humans before 2022

Analysis of monkeypox virus (MPXV) isolates circulating in Nigeria before the 2022 global outbreak of MPXV sheds light on the diversification of the virus that eventually gave rise to the 2022 MPXV lineage.

• Nnaemeka Ndodo
• , Jonathan Ashcroft
•  &  David O. Ulaeto

Article 21 August 2023 | Open Access

Postacute sequelae of COVID-19 at 2 years

Analysis of data from the US Department of Veterans Affairs showed that 2 years after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, risk for most postacute sequelae remained elevated in people who were hospitalized with COVID-19 but was attenuated in nonhospitalized individuals.

• Benjamin Bowe

Research Briefing | 20 June 2023

Local immune activation shapes systemic HIV reservoirs

In a person living with with human immunodeficiency virus (HIV), the recruitment of CD4 + T cells that recognize a co-pathogen in the central nervous system (CNS) resulted in localized inflammation and sparked HIV replication in the presence of suboptimal CNS anti-retroviral levels, leading to systemic virological failure. This case highlights the importance of considering inflammation and co-infection in HIV remission strategies.

Research Briefing | 27 February 2023

HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

We describe a 53-year-old man with HIV-1 who received allogeneic CCR5Δ32/Δ32 hematopoietic stem cell transplantation (HSCT) in 2013 to treat acute myeloid leukemia. Four years after analytic treatment interruption (ATI), the absence of viral rebound and the lack of immunological correlates of HIV-1 antigen persistence provide convincing evidence for HIV-1 cure.

Brief Communication 20 February 2023 | Open Access

In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

The recipient of an allogeneic stem cell transplant from a CCR5Δ32/Δ32 donor shows evidence of HIV type 1 cure, including the absence of a viral rebound over 4 years after stopping antiretroviral treatment.

• Björn-Erik Ole Jensen
• , Elena Knops
•  &  Guido Kobbe

Research Highlight | 09 February 2023

Viruses linked to neurodegenerative disease

Certain viruses — many of which have vaccines available — are linked to a significantly increased risk of neurodegenerative disease in the years following infection.

• Karen O’Leary

Research Highlight | 19 January 2023

Sex-specific effect of COVID-19 on the immune system

Mild COVID-19 changes the immune ‘set point’ and future response to vaccination against influenza — and does so in distinct ways for men versus women.

Article 18 January 2023 | Open Access

Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population

An analysis of sera samples collected between January and July of 2022 in Hong Kong shows that the effectiveness of both the BNT162b2 and CoronaVac COVID-19 vaccines against SARS-CoV-2 Omicron BA.2 variant infection waned rapidly after the third and fourth doses.

• Jonathan J. Lau
• , Samuel M. S. Cheng
•  &  Joseph T. Wu

Correspondence | 10 January 2023

An equitable route forward from China’s ‘zero COVID’ policy

• Zhicheng Wang
•  &  Yan Guo

Brief Communication | 06 December 2022

Low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1 and XBB.1 by parental mRNA vaccine or a BA.5 bivalent booster

Circulating variants of SARS-CoV-2 continue to evade neutralization by COVID-19 vaccines, including bivalent boosters that target the BA.4/BA.5 variants of concern, suggesting that strategies to get ahead of the virus’ evolution might be warranted.

• Chaitanya Kurhade
•  &  Pei‑Yong Shi

Article 10 November 2022 | Open Access

Acute and postacute sequelae associated with SARS-CoV-2 reinfection

A new analysis using US Department of Veterans Affairs databases showed that reinfection is associated with increased risk of all-cause mortality, hospitalization and a wide range of long COVID complications in individuals who have had SARS-CoV-2 compared to those with no reinfection.

Article | 20 October 2022

Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in mice

Bivalent vaccines elicit broad immune responses that neutralize ancestral SARS-CoV-2 and variants of concern and offer a customizable approach to protect from COVID-19 as new virus variants emerge.

• Suzanne M. Scheaffer
• , Diana Lee
•  &  Michael S. Diamond

Research Briefing | 03 October 2022

Long-term neurological sequelae of SARS-CoV-2 infection

We show that patients who survive the first 30 days of acute SARS-CoV-2 infection have an increased risk of various post-acute neurological disorders after 1 year compared with uninfected contemporaries. The burden of these sequelae (aspects of ‘long COVID’) has serious implications for patients as well as society.

Article 22 September 2022 | Open Access

Long-term neurologic outcomes of COVID-19

Individuals with COVID-19 are at an increased risk for an array of neurologic disorders at 12 months, even in those who were not hospitalized during the acute phase of the infection.

Research Briefing | 25 August 2022

Programmable antivirals to target conserved essential shapes in pandemic viral genomes

We identified and mapped at high-resolution RNA structures in viral genomes that are essential for virus reproduction. We then rapidly designed potent antivirals with high barriers to resistance that prevent or treat severe infections of these viruses with pandemic potential — via development of what we term ‘programmable antivirals’.

Article | 18 August 2022

Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2

Targeting conserved secondary structure of RNA viruses offers the potential for a customizable therapeutic approach to viral variants.

• Rachel J. Hagey
• , Menashe Elazar
•  &  Jeffrey S. Glenn

Correspondence | 13 July 2022

A prospective national cohort evaluating ring MVA vaccination as post-exposure prophylaxis for monkeypox

• Liem Binh Luong Nguyen
• , Jade Ghosn
•  &  Odile Launay

Research Briefing | 08 July 2022

Evolutionary insight into the emergence of SARS-CoV-2 variants of concern

Analysis of SARS-CoV-2 evolution during chronic infection reveals that in this setting, the virus evolves to bear mutations similar to those seen in variants of concern, and that many of these mutations are associated with antibody evasion. However, as mutations associated with high SARS-CoV-2 transmissibility are not observed, the emergence of variants of concern during chronic infection might be rare.

Article 20 June 2022 | Open Access

Drivers of adaptive evolution during chronic SARS-CoV-2 infections

Analysis of mutations that arise in chronic SARS-CoV-2 infections shows both overlap and differences with mutations present in pandemic viral variants of concern, highlighting their distinct drivers of evolution.

• Sheri Harari
• , Maayan Tahor
•  &  Adi Stern

News Feature | 13 June 2022

Africa’s outbreak sentinels

How monitoring wildlife can prevent the next pandemic

• Paul Adepoju

Comment | 30 May 2022

An early warning system for emerging SARS-CoV-2 variants

Global sequencing and surveillance capacity for SARS-CoV-2 must be strengthened and combined with multidisciplinary studies of infectivity, virulence and immune escape, in order to track the unpredictable evolution of the ongoing COVID-19 pandemic.

• Lorenzo Subissi
• , Anne von Gottberg
•  &  Anurag Agrawal

Research Highlight | 26 May 2022

The burden of unrecognized Ebola virus infection

People with less-severe Ebola virus disease may go undiagnosed, but they can still suffer long-term sequelae; this highlights the public health value of testing close contacts to identify and adequately treat all infections.

Article 25 May 2022 | Open Access

Long COVID after breakthrough SARS-CoV-2 infection

A new analysis using the US Department of Veterans Affairs national healthcare databases demonstrates that Long COVID can occur after breakthrough SARS-CoV-2 infection; however, the risk of death attributable to COVID and incidence of post-acute sequelae were substantially reduced (but not fully eliminated) compared to unvaccinated individuals.

• , Benjamin Bowe
•  &  Yan Xie

Research Highlight | 16 May 2022

Lullabies for long COVID

An online program developed in collaboration with the English National Opera could help with rehabilitation, by improving mental health and symptoms of breathlessness.

Article 12 May 2022 | Open Access

Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial

A combination of three monoclonal antibodies transiently reduced viremia in people living with HIV-1 and not on antiretroviral therapy, but it did not prevent viral rebound. Further studies are needed to determine if this approach can be optimized.

• , Kathryn E. Stephenson

Article | 08 April 2022

Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2

The infectious viral load of SARS-CoV-2 Omicron BA.1 is lower than that of Delta in symptomatic breakthrough infections of recipients of two doses of a COVID-19 vaccine, suggesting that the higher transmission of Omicron BA.1 is not linked to higher infectious viral load.

• Olha Puhach
• , Kenneth Adea
•  &  Benjamin Meyer

Research Highlight | 28 March 2022

Diabetes risk after COVID-19

Data reveal an increased risk of diabetes in the months after acute COVID-19 infection – which could have implications for stretched public health systems.

Article | 23 March 2022

Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies

Therapeutic antibodies, and sera from immunocompromised individuals prophylactically treated with therapeutic antibodies, differ in neutralizing activity against the SARS-CoV-2 Omicron BA.1 and BA.2 sublineages, which could have implications for pre-exposure and post-exposure treatment.

• Timothée Bruel
• , Jérôme Hadjadj
•  &  Olivier Schwartz

Research Highlight | 17 March 2022

Brain pathology of COVID-19

A large-scale study reveals infection-related structural changes in the brain — further research and long-term follow-up will be needed to determine their impact.

News | 15 March 2022

Russian COVID-19 vaccine in jeopardy after Ukraine invasion

Millions have received the first dose of Sputnik V, but sanctions against its Russian developer may prevent the rollout of second doses, which could leave them under-vaccinated

• Paul Webster

Research Highlight | 14 March 2022

Life-or-death decisions in a pandemic

A study involving physicians, politicians and the public tackles uncomfortable questions around who should be allocated lifesaving treatment.

News Feature | 11 March 2022

Africa prepares for endemic COVID-19

The pandemic is far from over in Africa, but there is also a funding gap in preparing for endemic COVID-19, which will require long-term investment in healthcare infrastructure.

Correspondence | 17 February 2022

More autopsy studies are needed to understand the pathogenesis of severe COVID-19

• Scott P. Layne
• , Kathie-Anne Walters
•  &  Jeffery K. Taubenberger

Article | 17 February 2022

Influenza virus infection history shapes antibody responses to influenza vaccination

Recent prior influenza A infection is associated with elevated hemagglutinin-inhibiting antibody responses and greater breadth of reactivity to influenza strains following vaccination, suggesting that infection history boosts vaccine responses.

• Maria Auladell
• , Hoang Vu Mai Phuong
•  &  Annette Fox

Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

Transcriptomic, proteomic and immune repertoire profiling reveals distinct peripheral features of MIS-C and pediatric COVID-19, including elevated soluble spike protein levels, more pronounced type II IFN-dependent gene expression and a higher B cell mutation rate in patients with MIS-C.

• Keith Sacco
• , Riccardo Castagnoli
•  &  Luigi D. Notarangelo

Article 14 February 2022 | Open Access

Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines

A large study in the United Kingdom shows that virus-specific antibody levels associated with at least 67% protection against SARS-CoV-2 Delta variant infection last longer after two doses of BNT162b2 vaccine than after two doses of ChAdOx1 vaccine in previously uninfected individuals.

• , Koen B. Pouwels
•  &  Chris Cunningham

News Feature | 11 February 2022

Health in the Amazon

Local communities protect the rainforest, but lack adequate healthcare.

• Sofia Moutinho

Article 07 February 2022 | Open Access

Long-term cardiovascular outcomes of COVID-19

Individuals with COVID-19 are at increased long-term risk for a wide range of cardiovascular disorders, even for individuals who were not hospitalized during the acute phase of the infection.

Article | 31 January 2022

Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial

An exploratory analysis of IL-15 superagonist treatment in people living with HIV and taking antiretroviral therapy shows increased T cell activation and viral transcription alongside a sustained reduction in inducible HIV provirus from blood cells.

• Jeffrey S. Miller
• , Zachary B. Davis
•  &  Timothy W. Schacker

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Call for papers, orthoflaviviruses: insights into molecular biology, epidemiology, and control, world aids day, coronaviruses: emerging and re-emerging pathogens in humans and animals.

Orthoflaviviruses, including Dengue, Zika, yellow fever, and West Nile viruses, are transmitted primarily by mosquitoes and ticks, causing significant health issues worldwide. Addressing the global burden of these viruses highlights the critical need for advanced prevention, treatment, and control strategies.  Currently open for submissions -  Submit Here

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Top Reviewers of 2023

A peer-reviewed journal would not survive without the generous time and insightful comments of the reviewers, whose efforts often go unrecognized. Although final decisions are always editorial, they are greatly facilitated by the deeper technical knowledge, scientific insights, understanding of social consequences, and passion that reviewers bring to our deliberations. For these reasons, the Editors and staff of  Virology Journal  would like to publicly acknowledge our top peer reviewers of 2023.

Erna Geessien Kroon, PhD, Universidade Federal de Minas Gerais, Brazil Tanushree Dangi, PhD, Northwestern University, USA Vincent Wong, MD, The Chinese University of Hong Kong, Hong Kong Ming-Lun Yeh, PhD, Kaohsiung Medical University, Taiwan Tatsuo Kanda, PhD, Nihon University, Japan Pedro Augusto Alves, PhD, Instituto René Rachou, Brazil Sobia Idrees, PhD, Centenary Institute and the University of Technology Sydney, Australia Selvaraj Pavulraj, PhD, Louisiana State University, USA Sara Ebrahimi, PhD, Deakin University, Australia Yoon-Seok Chung, PhD, Korea Disease Control and Prevention Agency (KDCA), South Korea Cigdem Alkan Yirci, PhD, The University of Texas Medical Branch, USA Chen Guang, PhD, Duke-NUS Medical School, Singapore Yao-Chun Hsu, PhD, I-Shou University, Taiwan

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Aims and scope

Virology Journal is an open access, peer reviewed journal that considers articles on all aspects of virology, including research on the viruses of animals, plants and microbes. The journal welcomes basic research as well as pre-clinical and clinical studies of novel diagnostic tools, vaccines and anti-viral therapies.

Journal Sections

Clinical Virology : Fred Kibenge, University of Prince Edward Island, Canada  Emerging viruses : Tom Geisbert,  University of Texas Medical Branch, USA Hepatitis viruses : Wan-Long Chuang,  Kaohsiung Medical University, Taiwan Herpes viruses : Tony Cunningham,  The Westmead Institute for Medical Research, Australia Influenza viruses : Hualan Chen,  Chinese Academy of Agricultural Sciences, China Negative-strand RNA viruses : John Barr,  University of Leeds, UK Other viruses : Erna Geessien Kroon,  Universidade Federal de Minas Gerais, Brazil Plant viruses : Supriya Chakraborty,  Jawaharlal Nehru University, India Positive-strand RNA viruses : Jaquelline Germano de Oliveira,  Fundação Oswaldo Cruz - Fiocruz, Brazil  Public health :  Kin On Kwok,  The Chinese University of Hong Kong Retroviruses : Aguinaldo Pinto, Universidade Federal de Santa Catarina, Brazil Veterinary DNA viruses : Walid Azab,  Freie Universität Berlin, Germany Veterinary RNA viruses : James Weger-Lucarelli,  Virginia Tech, USA Viruses of microbes : Joana Azeredo,  University of Minho, Portugal

Announcing the launch of In Review

Virology Journal , in partnership with Research Square, is now offering  In Review.  Authors choosing this free optional service will be able to:

• Share their work with fellow researchers to read, comment on, and cite even before publication
• Showcase their work to funders and others with a citable DOI while it is still under review
• Track their manuscript - including seeing when reviewers are invited, and when reports are received 

Alan McLachlan, Co-Editor-in-Chief

Alan McLachlan is a molecular geneticist and hepadnavirologist. He currently serves as a Professor in the Department of Microbiology and Immunology, University of Illinois Chicago, USA. His interests are focused on hepatitis viruses, primarily on hepatitis B virus (HBV) and its relationships to liver physiology.  His research is currently directed toward understanding the relationships between HBV transcription and viral biosynthesis using both cell culture and animal models.  His long-term goals include the identification of cellular gene products as targets for the development of small molecular weight antiviral compounds which, in combination with current nuceot(s)ide analog therapeutics, will resolve chronic HBV infections.

Leo Poon, Co-Editor-in-Chief

Leo Poon is a molecular virologist. He currently serves as a Professor in the School of Public Health, The University of Hong Kong and as a co-director of HKU-Pasteur Research Pole. He has strong interests in emerging viruses, including coronavirus and influenza virus. He researches on different aspects of these viruses, ranging from basic virology to clinical diagnosis. His ultimate goal is to use scientific findings to inform public health policy. Over the years, he has published about 290 peer-reviewed articles. Thus far, his work has been cited over 41,000 times and he has an H-index of 95 (Web of Science).

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Annual Journal Metrics

Citation Impact 2023 Journal Impact Factor: 4.0 5-year Journal Impact Factor: 3.8 Source Normalized Impact per Paper (SNIP): 0.971 SCImago Journal Rank (SJR): 1.016

Speed 2023 Submission to first editorial decision (median days): 8 Submission to acceptance (median days): 109

Usage 2023 Downloads: 2,323,860 Altmetric mentions: 11,783

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ISSN: 1743-422X

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